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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
25.45
Human Site:
S487
Identified Species:
43.08
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
S487
S
R
I
Q
R
P
F
S
V
K
F
D
P
Y
T
Chimpanzee
Pan troglodytes
XP_508221
618
67613
S577
S
R
I
Q
R
P
F
S
V
K
F
D
P
Y
T
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
Y450
F
S
V
Y
F
N
P
Y
T
Q
S
I
E
I
L
Dog
Lupus familis
XP_855547
495
55650
S454
S
R
I
Q
R
P
F
S
V
K
F
D
P
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
S457
S
R
I
Q
R
P
F
S
V
K
F
D
P
Y
T
Rat
Rattus norvegicus
P04177
498
55948
S457
S
R
I
Q
R
P
F
S
V
K
F
D
P
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
S527
S
T
I
P
R
P
F
S
V
R
Y
D
P
Y
T
Chicken
Gallus gallus
P70080
445
51121
Y405
F
G
V
K
Y
N
P
Y
T
Q
S
V
Q
I
L
Frog
Xenopus laevis
Q92142
481
55388
F441
F
G
L
K
Y
N
P
F
T
Q
S
V
D
I
L
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
V449
R
I
K
R
P
F
S
V
R
F
D
P
Y
T
D
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
Y436
K
R
P
F
A
V
R
Y
E
P
F
T
C
T
V
Fruit Fly
Dros. melanogaster
P18459
579
65977
E535
S
T
M
S
R
P
F
E
V
R
F
N
P
H
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
Y417
F
Q
I
R
Y
N
A
Y
T
Q
R
V
E
I
L
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
N481
M
K
M
A
R
P
Y
N
V
R
Y
D
P
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
73.3
0
0
0
13.3
53.3
N.A.
6.6
46.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
86.6
20
20
6.6
13.3
80
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
50
8
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
0
0
15
0
0
% E
% Phe:
29
0
0
8
8
8
50
8
0
8
50
0
0
0
0
% F
% Gly:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
50
0
0
0
0
0
0
0
0
8
0
29
0
% I
% Lys:
8
8
8
15
0
0
0
0
0
36
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
29
% L
% Met:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
29
0
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
8
8
58
22
0
0
8
0
8
58
0
0
% P
% Gln:
0
8
0
36
0
0
0
0
0
29
0
0
8
0
0
% Q
% Arg:
8
43
0
15
58
0
8
0
8
22
8
0
0
0
0
% R
% Ser:
50
8
0
8
0
0
8
43
0
0
22
0
0
0
0
% S
% Thr:
0
15
0
0
0
0
0
0
29
0
0
8
0
15
58
% T
% Val:
0
0
15
0
0
8
0
8
58
0
0
22
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
22
0
8
29
0
0
15
0
8
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _